2022
Waśkiel-Burnat, Anna; Kotowska, Maja; Dorobek, Wioleta; Smyk, Julia Maria; Gąsecka, Aleksandra; Niemczyk, Anna; Blicharz, Leszek; Filipiak, Krzysztof Jerzy; Olszewska, Małgorzata; Rudnicka, Lidia
Patients with alopecia areata are at risk of endothelial dysfunction: results of a case–control study Journal Article
In: Clinical and Experimental Dermatology, vol. 47, no. 8, pp. 1517–1522, 2022, ISSN: 1365-2230, 0307-6938.
@article{waskiel-burnat_patients_2022,
title = {Patients with alopecia areata are at risk of endothelial dysfunction: results of a case–control study},
author = {Anna Waśkiel-Burnat and Maja Kotowska and Wioleta Dorobek and Julia Maria Smyk and Aleksandra Gąsecka and Anna Niemczyk and Leszek Blicharz and Krzysztof Jerzy Filipiak and Małgorzata Olszewska and Lidia Rudnicka},
url = {https://academic.oup.com/ced/article/47/8/1517/6692911},
doi = {10.1111/ced.15206},
issn = {1365-2230, 0307-6938},
year = {2022},
date = {2022-08-01},
urldate = {2024-10-28},
journal = {Clinical and Experimental Dermatology},
volume = {47},
number = {8},
pages = {1517–1522},
abstract = {Abstract
Background
Alopecia areata (AA) is an autoimmune form of hair loss, which may affect any hair-bearing area. It has been suggested that AA is associated with an increased risk of metabolic and cardiovascular comorbidities.
Aim
To evaluate the early predictors of cardiovascular disease [endothelial function (EF) and arterial stiffness (AS)] in patients with AA without prior cardiovascular disease, and compare with healthy controls (HCs).
Methods In total, 52 patients with AA (38 women and 14 men; mean age 41 years, range 30–52 years) and 34 HCs, matched for age, sex and body mass index, were enrolled in the study. EF, expressed as reactive hyperaemia index (RHI), and AS, identified by augmentation index at 75 beats/min (AI@75) were assessed with the use of the Endo-PAT 2000 device. Endothelial dysfunction (ED) was defined as RHI value ≤1.67.
Results ED was observed in 22 of 52 patients with AA (42%) and in 4 of 34 HCs (12%) (P < 0.01). Moreover, mean RHI was lower in patients with AA compared with HCs (1.90 ± 0.31 vs. 2.11 ± 0.45; P = 0.03). There was no significant difference in AI@75 between patients with AA and HCs.
Conclusions
Patients with AA show abnormalities in early predictors of cardiovascular diseases. Regular cardiovascular screening might be appropriate for patients with AA.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Abstract
Background
Alopecia areata (AA) is an autoimmune form of hair loss, which may affect any hair-bearing area. It has been suggested that AA is associated with an increased risk of metabolic and cardiovascular comorbidities.
Aim
To evaluate the early predictors of cardiovascular disease [endothelial function (EF) and arterial stiffness (AS)] in patients with AA without prior cardiovascular disease, and compare with healthy controls (HCs).
Methods In total, 52 patients with AA (38 women and 14 men; mean age 41 years, range 30–52 years) and 34 HCs, matched for age, sex and body mass index, were enrolled in the study. EF, expressed as reactive hyperaemia index (RHI), and AS, identified by augmentation index at 75 beats/min (AI@75) were assessed with the use of the Endo-PAT 2000 device. Endothelial dysfunction (ED) was defined as RHI value ≤1.67.
Results ED was observed in 22 of 52 patients with AA (42%) and in 4 of 34 HCs (12%) (P < 0.01). Moreover, mean RHI was lower in patients with AA compared with HCs (1.90 ± 0.31 vs. 2.11 ± 0.45; P = 0.03). There was no significant difference in AI@75 between patients with AA and HCs.
Conclusions
Patients with AA show abnormalities in early predictors of cardiovascular diseases. Regular cardiovascular screening might be appropriate for patients with AA.
Background
Alopecia areata (AA) is an autoimmune form of hair loss, which may affect any hair-bearing area. It has been suggested that AA is associated with an increased risk of metabolic and cardiovascular comorbidities.
Aim
To evaluate the early predictors of cardiovascular disease [endothelial function (EF) and arterial stiffness (AS)] in patients with AA without prior cardiovascular disease, and compare with healthy controls (HCs).
Methods In total, 52 patients with AA (38 women and 14 men; mean age 41 years, range 30–52 years) and 34 HCs, matched for age, sex and body mass index, were enrolled in the study. EF, expressed as reactive hyperaemia index (RHI), and AS, identified by augmentation index at 75 beats/min (AI@75) were assessed with the use of the Endo-PAT 2000 device. Endothelial dysfunction (ED) was defined as RHI value ≤1.67.
Results ED was observed in 22 of 52 patients with AA (42%) and in 4 of 34 HCs (12%) (P < 0.01). Moreover, mean RHI was lower in patients with AA compared with HCs (1.90 ± 0.31 vs. 2.11 ± 0.45; P = 0.03). There was no significant difference in AI@75 between patients with AA and HCs.
Conclusions
Patients with AA show abnormalities in early predictors of cardiovascular diseases. Regular cardiovascular screening might be appropriate for patients with AA.
Kubica, Jacek; Adamski, Piotr; Ładny, Jerzy R.; Kaźmierczak, Jarosław; Fabiszak, Tomasz; Filipiak, Krzysztof J.; Gajda, Robert; Gąsior, Mariusz; Gąsior, Zbigniew; Gil, Robert; Gorący, Jarosław; Grajek, Stefan; Gromadziński, Leszek; Gruchała, Marcin; Grześk, Grzegorz; Hoffman, Piotr; Jaguszewski, Miłosz J.; Janion, Marianna; Jankowski, Piotr; Kalarus, Zbigniew; Kasprzak, Jarosław D.; Kleinrok, Andrzej; Kochman, Wacław; Kubica, Aldona; Kuliczkowski, Wiktor; Legutko, Jacek; Lesiak, Maciej; Nadolny, Klaudiusz; Navarese, Eliano P.; Niezgoda, Piotr; Ostrowska, Małgorzata; Paciorek, Przemysław; Siller-Matula, Jolanta; Szarpak, Łukasz; Timler, Dariusz; Witkowski, Adam; Wojakowski, Wojciech; Wysokiński, Andrzej; Zielińska, Marzenna
Pre-hospital treatment of patients with acute coronary syndrome: Recommendations for medical emergency teams. Expert position update 2022 Journal Article
In: Cardiology Journal, vol. 29, no. 4, pp. 540–552, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{kubica_pre-hospital_2022,
title = {Pre-hospital treatment of patients with acute coronary syndrome: Recommendations for medical emergency teams. Expert position update 2022},
author = {Jacek Kubica and Piotr Adamski and Jerzy R. Ładny and Jarosław Kaźmierczak and Tomasz Fabiszak and Krzysztof J. Filipiak and Robert Gajda and Mariusz Gąsior and Zbigniew Gąsior and Robert Gil and Jarosław Gorący and Stefan Grajek and Leszek Gromadziński and Marcin Gruchała and Grzegorz Grześk and Piotr Hoffman and Miłosz J. Jaguszewski and Marianna Janion and Piotr Jankowski and Zbigniew Kalarus and Jarosław D. Kasprzak and Andrzej Kleinrok and Wacław Kochman and Aldona Kubica and Wiktor Kuliczkowski and Jacek Legutko and Maciej Lesiak and Klaudiusz Nadolny and Eliano P. Navarese and Piotr Niezgoda and Małgorzata Ostrowska and Przemysław Paciorek and Jolanta Siller-Matula and Łukasz Szarpak and Dariusz Timler and Adam Witkowski and Wojciech Wojakowski and Andrzej Wysokiński and Marzenna Zielińska},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/88281},
doi = {10.5603/cj.a2022.0026},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-07-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {4},
pages = {540–552},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Sobierajski, Tomasz; Surma, Stanisław; Romańczyk, Monika; Łabuzek, Krzysztof; Filipiak, Krzysztof J.; Oparil, Suzanne
What Is or What Is Not a Risk Factor for Arterial Hypertension? Not Hamlet, but Medical Students Answer That Question Journal Article
In: International Journal of Environmental Research and Public Health, vol. 19, no. 13, pp. 8206, 2022, ISSN: 1660-4601.
@article{sobierajski_what_2022,
title = {What Is or What Is Not a Risk Factor for Arterial Hypertension? Not Hamlet, but Medical Students Answer That Question},
author = {Tomasz Sobierajski and Stanisław Surma and Monika Romańczyk and Krzysztof Łabuzek and Krzysztof J. Filipiak and Suzanne Oparil},
url = {https://www.mdpi.com/1660-4601/19/13/8206},
doi = {10.3390/ijerph19138206},
issn = {1660-4601},
year = {2022},
date = {2022-07-01},
urldate = {2024-10-28},
journal = {International Journal of Environmental Research and Public Health},
volume = {19},
number = {13},
pages = {8206},
abstract = {Hypertension is a leading cause of cardiovascular disease and premature death worldwide. The most important method of preventing hypertension is social awareness of its causes. An important role in educating society about hypertension is played by medical personnel. The study involved 327 students of medicine representing all years of study. The study used a proprietary questionnaire containing test questions about knowledge of the causes of hypertension (classical and non-classical factors), as well as questionable and false risk factors for the disease. The students’ knowledge of the complications of hypertension was also assessed. Most of the students rated their knowledge about hypertension as good. Classical risk factors for hypertension were identified by students in all years of study: I–III and IV–VI. Non-classical risk factors for hypertension were less often identified by the students. The students almost unanimously indicated that the complications of hypertension include heart failure, heart attack, stroke, aortic aneurysm, kidney failure, atherosclerosis, eye diseases and worse prognosis in COVID-19. Students’ knowledge of the causes of hypertension increased during medical studies. The knowledge of the respondents about classical risk factors for hypertension was extensive, whereas knowledge of non-classical risk factors it was insufficient. Most of the respondents were well aware of the complications of hypertension. Some students identified some factors incorrectly as increasing the risk of hypertension. Emphasis should be placed on the dissemination of knowledge about non-classical hypertension risk factors to medical students.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hypertension is a leading cause of cardiovascular disease and premature death worldwide. The most important method of preventing hypertension is social awareness of its causes. An important role in educating society about hypertension is played by medical personnel. The study involved 327 students of medicine representing all years of study. The study used a proprietary questionnaire containing test questions about knowledge of the causes of hypertension (classical and non-classical factors), as well as questionable and false risk factors for the disease. The students’ knowledge of the complications of hypertension was also assessed. Most of the students rated their knowledge about hypertension as good. Classical risk factors for hypertension were identified by students in all years of study: I–III and IV–VI. Non-classical risk factors for hypertension were less often identified by the students. The students almost unanimously indicated that the complications of hypertension include heart failure, heart attack, stroke, aortic aneurysm, kidney failure, atherosclerosis, eye diseases and worse prognosis in COVID-19. Students’ knowledge of the causes of hypertension increased during medical studies. The knowledge of the respondents about classical risk factors for hypertension was extensive, whereas knowledge of non-classical risk factors it was insufficient. Most of the respondents were well aware of the complications of hypertension. Some students identified some factors incorrectly as increasing the risk of hypertension. Emphasis should be placed on the dissemination of knowledge about non-classical hypertension risk factors to medical students.
Blek, Natasza; Szwed, Piotr; Putowska, Paulina; Nowicka, Adrianna; Drela, Wiktoria L.; Gasecka, Aleksandra; Ladny, Jerzy R.; Merza, Yaroslaw; Jaguszewski, Milosz J.; Szarpak, Lukasz
In: Cardiology Journal, vol. 29, no. 4, pp. 610–618, 2022, ISSN: 1898-018X, 1897-5593.
@article{blek_diagnostic_2022,
title = {The diagnostic and prognostic value of copeptin in patients with acute ischemic stroke and transient ischemic attack: A systematic review and meta-analysis},
author = {Natasza Blek and Piotr Szwed and Paulina Putowska and Adrianna Nowicka and Wiktoria L. Drela and Aleksandra Gasecka and Jerzy R. Ladny and Yaroslaw Merza and Milosz J. Jaguszewski and Lukasz Szarpak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/89521},
doi = {10.5603/CJ.a2022.0045},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-07-01},
urldate = {2024-10-28},
journal = {Cardiology Journal},
volume = {29},
number = {4},
pages = {610–618},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gąsecka, Aleksandra; Rzepa, Łukasz; Konwerski, Michał; Zawadzka, Magdalena; Wysocki, Karol; Budnik, Monika; Czub, Paweł; Wilimski, Radosław; Wondołkowski, Mateusz; Wilczyńska-Burlikowska, Joanna; Scisło, Piotr; Konop, Marek; Huczek, Zenon; Kochman, Janusz; Kochanowski, Janusz; Opolski, Grzegorz; Filipiak, Krzysztof J.; Ufnal, Marcin; Kapłon-Cieślicka, Agnieszka
In: Cardiology Journal, vol. 29, no. 4, pp. 691–697, 2022, ISSN: 1898-018X, 1897-5593.
@article{gasecka_trimethylamine-n-oxide_2022,
title = {Trimethylamine-N-oxide (TMAO) versus echocardiographic, biochemical and histopathological indices of heart failure in patients with severe aortic stenosis: Rationale and design of the prospective, observational TASTE study},
author = {Aleksandra Gąsecka and Łukasz Rzepa and Michał Konwerski and Magdalena Zawadzka and Karol Wysocki and Monika Budnik and Paweł Czub and Radosław Wilimski and Mateusz Wondołkowski and Joanna Wilczyńska-Burlikowska and Piotr Scisło and Marek Konop and Zenon Huczek and Janusz Kochman and Janusz Kochanowski and Grzegorz Opolski and Krzysztof J. Filipiak and Marcin Ufnal and Agnieszka Kapłon-Cieślicka},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/87256},
doi = {10.5603/CJ.a2022.0023},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-07-01},
urldate = {2024-10-28},
journal = {Cardiology Journal},
volume = {29},
number = {4},
pages = {691–697},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Strózik, Mateusz; Szarpak, Lukasz; Adam, Ishag; Smereka, Jacek
Determinants of Place of Delivery during the COVID-19 Pandemic—Internet Survey in Polish Pregnant Women Journal Article
In: Medicina, vol. 58, no. 6, pp. 831, 2022, ISSN: 1648-9144, (Publisher: MDPI AG).
@article{strozik_determinants_2022,
title = {Determinants of Place of Delivery during the COVID-19 Pandemic—Internet Survey in Polish Pregnant Women},
author = {Mateusz Strózik and Lukasz Szarpak and Ishag Adam and Jacek Smereka},
url = {https://www.mdpi.com/1648-9144/58/6/831},
doi = {10.3390/medicina58060831},
issn = {1648-9144},
year = {2022},
date = {2022-06-01},
urldate = {2024-09-17},
journal = {Medicina},
volume = {58},
number = {6},
pages = {831},
abstract = {Background and Objectives: COVID-19 is a pandemic disease, and its unpredictable outcome makes it particularly dangerous, especially for pregnant women. One of the decisions they have to make is where they will give birth. This study aimed to determine the factors influencing the choice of place of delivery and the impact of the COVID 19 pandemic on these factors. Materials and Methods: The study was conducted on 517 respondents from Poland. The research methods comprised the authors’ own survey questionnaire distributed via the Internet from 8 to 23 June 2021. The survey was fully anonymous, voluntary, and addressed to women who gave birth during the pandemic or will give birth shortly. Results: A total of 440 (85.1%) respondents were afraid of SARS-CoV-2 infection. The most frequently indicated factors were fear of complications in the newborn, fear of intrauterine fetal death, and congenital disabilities in a newborn. A total of 74 (14.3%) women considered home delivery. The main factors that discouraged the choice of home birth were the lack of professional medical care 73.1% (N = 378), the lack of anesthesia 23.6% (N = 122), and the presence of indications for caesarean section 23.4% (N = 121). The possibility of mother–child isolation caused the greatest fear about hospital delivery. During the COVID-19 pandemic, pregnant women concerned about SARS-CoV-2 infection were more likely to consider home delivery than those without such fears. The most important factors affecting the choice of the place of delivery included the possibility of a partner’s presence, excellent sanitary conditions and optimal distance from the hospital, and the availability of epidural analgesia for delivery. Conclusions: Our study identifies the determinants of place of delivery during the COVID-19 pandemic. The data we obtained can result in the healthcare system considering patients’ needs in case of similar crisis in the future.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background and Objectives: COVID-19 is a pandemic disease, and its unpredictable outcome makes it particularly dangerous, especially for pregnant women. One of the decisions they have to make is where they will give birth. This study aimed to determine the factors influencing the choice of place of delivery and the impact of the COVID 19 pandemic on these factors. Materials and Methods: The study was conducted on 517 respondents from Poland. The research methods comprised the authors’ own survey questionnaire distributed via the Internet from 8 to 23 June 2021. The survey was fully anonymous, voluntary, and addressed to women who gave birth during the pandemic or will give birth shortly. Results: A total of 440 (85.1%) respondents were afraid of SARS-CoV-2 infection. The most frequently indicated factors were fear of complications in the newborn, fear of intrauterine fetal death, and congenital disabilities in a newborn. A total of 74 (14.3%) women considered home delivery. The main factors that discouraged the choice of home birth were the lack of professional medical care 73.1% (N = 378), the lack of anesthesia 23.6% (N = 122), and the presence of indications for caesarean section 23.4% (N = 121). The possibility of mother–child isolation caused the greatest fear about hospital delivery. During the COVID-19 pandemic, pregnant women concerned about SARS-CoV-2 infection were more likely to consider home delivery than those without such fears. The most important factors affecting the choice of the place of delivery included the possibility of a partner’s presence, excellent sanitary conditions and optimal distance from the hospital, and the availability of epidural analgesia for delivery. Conclusions: Our study identifies the determinants of place of delivery during the COVID-19 pandemic. The data we obtained can result in the healthcare system considering patients’ needs in case of similar crisis in the future.
Pietrasik, Arkadiusz; Gąsecka, Aleksandra; Szarpak, Łukasz; Pruc, Michał; Kopiec, Tomasz; Darocha, Szymon; Banaszkiewicz, Marta; Niewada, Maciej; Grabowski, Marcin; Kurzyna, Marcin
In: Frontiers in Cardiovascular Medicine, vol. 9, 2022, ISSN: 2297-055X, (Publisher: Frontiers Media SA).
@article{pietrasik_catheter-based_2022,
title = {Catheter-Based Therapies Decrease Mortality in Patients With Intermediate and High-Risk Pulmonary Embolism: Evidence From Meta-Analysis of 65,589 Patients},
author = {Arkadiusz Pietrasik and Aleksandra Gąsecka and Łukasz Szarpak and Michał Pruc and Tomasz Kopiec and Szymon Darocha and Marta Banaszkiewicz and Maciej Niewada and Marcin Grabowski and Marcin Kurzyna},
url = {https://www.frontiersin.org/articles/10.3389/fcvm.2022.861307/full},
doi = {10.3389/fcvm.2022.861307},
issn = {2297-055X},
year = {2022},
date = {2022-06-01},
urldate = {2024-09-17},
journal = {Frontiers in Cardiovascular Medicine},
volume = {9},
abstract = {BackgroundCatheter-directed therapies (CDT) are an alternative to systemic thrombolysis (ST) in pulmonary embolism (PE) patients, but the mortality benefit of CDT is unclear.ObjectiveWe conducted a systematic review with meta-analysis to compare the efficacy and safety of CDT and ST in intermediate-high and high-risk PE.MethodsWe included (P) participants, adult PE patients; (I) intervention, CDT; (C) comparison, ST; (O) outcomes, mortality, complications, in-hospital treatment, and length of hospital stay; (S) study design, randomized controlled trials (RCTs), or cohort comparing CDT and ST. The primary endpoint was 30-day mortality. Secondary outcomes included treatment-related complications including bleeding, the use of hospital resources, and length of hospital stay.ResultsEleven studies including 65,589 patients met the inclusion criteria. Thirty-day mortality was lower in the CDT group, compared to ST group [7.3 vs. 13.6%; odds ratio (OR) = 0.51, 95% confidence interval (CI) 0.38–0.69, p < 0.001]. The rates of myocardial injury, cardiac arrest, and stroke were lower in CDT group, compared to ST group (p < 0.001 for all). The rates of any major bleeding, intracranial hemorrhage, hemoptysis, and red blood cell transfusion were lower in patients treated with CDT, compared to ST (p ≤ 0.01 for all). Extracorporeal life support was used more often in patients treated with CDT, compared to ST (0.5 vs. 0.2%},
note = {Publisher: Frontiers Media SA},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BackgroundCatheter-directed therapies (CDT) are an alternative to systemic thrombolysis (ST) in pulmonary embolism (PE) patients, but the mortality benefit of CDT is unclear.ObjectiveWe conducted a systematic review with meta-analysis to compare the efficacy and safety of CDT and ST in intermediate-high and high-risk PE.MethodsWe included (P) participants, adult PE patients; (I) intervention, CDT; (C) comparison, ST; (O) outcomes, mortality, complications, in-hospital treatment, and length of hospital stay; (S) study design, randomized controlled trials (RCTs), or cohort comparing CDT and ST. The primary endpoint was 30-day mortality. Secondary outcomes included treatment-related complications including bleeding, the use of hospital resources, and length of hospital stay.ResultsEleven studies including 65,589 patients met the inclusion criteria. Thirty-day mortality was lower in the CDT group, compared to ST group [7.3 vs. 13.6%; odds ratio (OR) = 0.51, 95% confidence interval (CI) 0.38–0.69, p < 0.001]. The rates of myocardial injury, cardiac arrest, and stroke were lower in CDT group, compared to ST group (p < 0.001 for all). The rates of any major bleeding, intracranial hemorrhage, hemoptysis, and red blood cell transfusion were lower in patients treated with CDT, compared to ST (p ≤ 0.01 for all). Extracorporeal life support was used more often in patients treated with CDT, compared to ST (0.5 vs. 0.2%
Szarpak, Lukasz; Szwed, Piotr; Gasecka, Aleksandra; Rafique, Zubaid; Pruc, Michal; Filipiak, Krzysztof J.; Jaguszewski, Milosz J.
Milrinone or dobutamine in patients with heart failure: evidence from meta‐analysis Journal Article
In: ESC Heart Failure, vol. 9, no. 3, pp. 2049–2050, 2022, ISSN: 2055-5822, 2055-5822, (Publisher: Wiley).
@article{szarpak_milrinone_2022,
title = {Milrinone or dobutamine in patients with heart failure: evidence from meta‐analysis},
author = {Lukasz Szarpak and Piotr Szwed and Aleksandra Gasecka and Zubaid Rafique and Michal Pruc and Krzysztof J. Filipiak and Milosz J. Jaguszewski},
url = {https://onlinelibrary.wiley.com/doi/10.1002/ehf2.13812},
doi = {10.1002/ehf2.13812},
issn = {2055-5822, 2055-5822},
year = {2022},
date = {2022-06-01},
urldate = {2024-09-17},
journal = {ESC Heart Failure},
volume = {9},
number = {3},
pages = {2049–2050},
note = {Publisher: Wiley},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Jaguszewski, Milosz J.; Pruc, Michal; Malysz, Marek; Gasecka, Aleksandra; Rafique, Zubaid
Safety and efficacy of clopidogrel versus ticagrelor in acute coronary syndrome in the prehospital setting Journal Article
In: The American Journal of Emergency Medicine, vol. 56, pp. 351–352, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{szarpak_safety_2022,
title = {Safety and efficacy of clopidogrel versus ticagrelor in acute coronary syndrome in the prehospital setting},
author = {Lukasz Szarpak and Milosz J. Jaguszewski and Michal Pruc and Marek Malysz and Aleksandra Gasecka and Zubaid Rafique},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721007671},
doi = {10.1016/j.ajem.2021.09.032},
issn = {0735-6757},
year = {2022},
date = {2022-06-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {56},
pages = {351–352},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Pruc, Michal; Maslyukov, Anatoliy; Glamcevski, Mihajlo T.; Gilis-Malinowska, Natasza; Jaguszewski, Milosz J.
Genesis of arrhythmia in the course of COVID-19 Journal Article
In: Cardiology Journal, vol. 29, no. 3, pp. 535–536, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{szarpak_genesis_2022,
title = {Genesis of arrhythmia in the course of COVID-19},
author = {Lukasz Szarpak and Michal Pruc and Anatoliy Maslyukov and Mihajlo T. Glamcevski and Natasza Gilis-Malinowska and Milosz J. Jaguszewski},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/89641},
doi = {10.5603/cj.a2022.0028},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-05-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {3},
pages = {535–536},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
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Savytskyi, Ivan Volodymyrovych; Pruc, Michal; Malysz, Marek; Maslyukov, Anatoliy; Szarpak, Lukasz
Post-COVID-19 postural orthostatic tachycardia syndrome Journal Article
In: Cardiology Journal, vol. 29, no. 3, pp. 531–532, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{savytskyi_post-covid-19_2022,
title = {Post-COVID-19 postural orthostatic tachycardia syndrome},
author = {Ivan Volodymyrovych Savytskyi and Michal Pruc and Marek Malysz and Anatoliy Maslyukov and Lukasz Szarpak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/89247},
doi = {10.5603/cj.a2022.0021},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-05-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {3},
pages = {531–532},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Pruc, Michal; Merza, Yaroslaw; Filipiak, Krzysztof J.; Navolokin, Ihor; Szarpak, Lukasz
Treatment prospects for post-COVID-19 cardiac patients Journal Article
In: Cardiology Journal, vol. 29, no. 3, pp. 533–534, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{pruc_treatment_2022,
title = {Treatment prospects for post-COVID-19 cardiac patients},
author = {Michal Pruc and Yaroslaw Merza and Krzysztof J. Filipiak and Ihor Navolokin and Lukasz Szarpak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/89421},
doi = {10.5603/cj.a2022.0022},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-05-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {3},
pages = {533–534},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Safiejko, Kamil; Smereka, Jacek; Filipiak, Krzysztof J.; Szarpak, Agnieszka; Dabrowski, Marek; Ladny, Jerzy R.; Jaguszewski, Milosz J.; Szarpak, Lukasz
In: Cardiology Journal, vol. 29, no. 3, pp. 463–471, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{safiejko_effectiveness_2022,
title = {Effectiveness and safety of hypotension fluid resuscitation in traumatic hemorrhagic shock: A systematic review and meta-analysis of randomized controlled trials},
author = {Kamil Safiejko and Jacek Smereka and Krzysztof J. Filipiak and Agnieszka Szarpak and Marek Dabrowski and Jerzy R. Ladny and Milosz J. Jaguszewski and Lukasz Szarpak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/69677},
doi = {10.5603/cj.a2020.0096},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-05-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {3},
pages = {463–471},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Filipiak, Krzysztof J.; Surma, Stanisław; Romańczyk, Monika; Okopień, Bogusław
Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10 Journal Article
In: Journal of Cardiovascular Development and Disease, vol. 9, no. 5, pp. 161, 2022, ISSN: 2308-3425.
@article{filipiak_heart_2022,
title = {Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10},
author = {Krzysztof J. Filipiak and Stanisław Surma and Monika Romańczyk and Bogusław Okopień},
url = {https://www.mdpi.com/2308-3425/9/5/161},
doi = {10.3390/jcdd9050161},
issn = {2308-3425},
year = {2022},
date = {2022-05-01},
urldate = {2024-10-28},
journal = {Journal of Cardiovascular Development and Disease},
volume = {9},
number = {5},
pages = {161},
abstract = {Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely on highly effective drugs that improve prognosis and prolong life. Currently, the ESC guidelines from 2021 indicate that ACEI, ARNI, BB, and SGLT2 inhibitors are the first-line drugs in HF. It is also worth remembering that the use of coenzyme Q10 brought many benefits in patients with HF. Coenzyme Q10 is a very important compound that performs many functions in the human body. The most important function of coenzyme Q10 is participation in the production of energy in the mitochondria, which determines the proper functioning of all cells, tissues, and organs. The highest concentration of coenzyme Q10 is found in the tissue of the heart muscle. As the body ages, the concentration of coenzyme Q10 in the tissue of the heart muscle decreases, which makes it more susceptible to damage by free radicals. It has been shown that in patients with HF, the aggravation of disease symptoms is inversely related to the concentration of coenzyme Q10. Importantly, the concentration of coenzyme Q10 in patients with HF was an important predictor of the risk of death. Long-term coenzyme Q10 supplementation at a dose of 300 mg/day (Q-SYMBIO study) has been shown to significantly improve heart function and prognosis in patients with HF. This article summarizes the latest and most important data on CoQ10 in pathogenesis.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely on highly effective drugs that improve prognosis and prolong life. Currently, the ESC guidelines from 2021 indicate that ACEI, ARNI, BB, and SGLT2 inhibitors are the first-line drugs in HF. It is also worth remembering that the use of coenzyme Q10 brought many benefits in patients with HF. Coenzyme Q10 is a very important compound that performs many functions in the human body. The most important function of coenzyme Q10 is participation in the production of energy in the mitochondria, which determines the proper functioning of all cells, tissues, and organs. The highest concentration of coenzyme Q10 is found in the tissue of the heart muscle. As the body ages, the concentration of coenzyme Q10 in the tissue of the heart muscle decreases, which makes it more susceptible to damage by free radicals. It has been shown that in patients with HF, the aggravation of disease symptoms is inversely related to the concentration of coenzyme Q10. Importantly, the concentration of coenzyme Q10 in patients with HF was an important predictor of the risk of death. Long-term coenzyme Q10 supplementation at a dose of 300 mg/day (Q-SYMBIO study) has been shown to significantly improve heart function and prognosis in patients with HF. This article summarizes the latest and most important data on CoQ10 in pathogenesis.
Czech, Marcin; Boguslawski, Stefan; Smaga, Anna; Filipiak, Krzysztof J.
In: Cardiology Journal, vol. 29, no. 3, pp. 405–412, 2022, ISSN: 1898-018X, 1897-5593.
@article{czech_use_2022,
title = {Use of single pill combinations in the treatment of arterial hypertension in Poland: The current practice and guidelines, the impact on reimbursement spending and patient co-payment},
author = {Marcin Czech and Stefan Boguslawski and Anna Smaga and Krzysztof J. Filipiak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/86583},
doi = {10.5603/CJ.a2022.0031},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-05-01},
urldate = {2024-10-28},
journal = {Cardiology Journal},
volume = {29},
number = {3},
pages = {405–412},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Blek, Natasza; Szarpak, Lukasz; Ladny, Jerzy Robert
Effect of the COVID-19 Pandemic in the Prehospital Management of Patients with Suspected Acute Stroke: A Retrospective Cohort Study Journal Article
In: International Journal of Environmental Research and Public Health, vol. 19, no. 8, pp. 4769, 2022, ISSN: 1660-4601, (Publisher: MDPI AG).
@article{blek_effect_2022,
title = {Effect of the COVID-19 Pandemic in the Prehospital Management of Patients with Suspected Acute Stroke: A Retrospective Cohort Study},
author = {Natasza Blek and Lukasz Szarpak and Jerzy Robert Ladny},
url = {https://www.mdpi.com/1660-4601/19/8/4769},
doi = {10.3390/ijerph19084769},
issn = {1660-4601},
year = {2022},
date = {2022-04-01},
urldate = {2024-09-17},
journal = {International Journal of Environmental Research and Public Health},
volume = {19},
number = {8},
pages = {4769},
abstract = {Acute Ischemic Stroke (AIS) can be successfully handled if it is noticed early in the prehospital setting and immediately diagnosed in the emergency department (ED). The coronavirus pandemic has altered the way health care is delivered and has had a profound impact on healthcare delivery. The effects could include prioritizing the prevention of COVID-19 spread, which could result in the discontinuation or deferral of non-COVID-19 care. We used the National Emergency Medical Service Command Support System, a register of medical interventions performed by emergency medical services (EMS) in Poland, to assess the impact of the COVID-19 epidemic across the Masovian Voivodeship on suspected stroke patients’ baseline characteristics, prehospital vital parameters, clinical and neurological status, emergency procedures performed on the prehospital phase and EMS processing times. Between 1 April 2019 and 30 April 2021, the study population included 18,922 adult suspected stroke patients who were treated by EMS teams, with 18,641 admitted to the emergency departments. The overall number of suspected stroke patients treated by EMS remained unchanged during COVID-19 compared to the pre-COVID-19 period; however, the average time from call to hospital admission increased by 15 min.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Acute Ischemic Stroke (AIS) can be successfully handled if it is noticed early in the prehospital setting and immediately diagnosed in the emergency department (ED). The coronavirus pandemic has altered the way health care is delivered and has had a profound impact on healthcare delivery. The effects could include prioritizing the prevention of COVID-19 spread, which could result in the discontinuation or deferral of non-COVID-19 care. We used the National Emergency Medical Service Command Support System, a register of medical interventions performed by emergency medical services (EMS) in Poland, to assess the impact of the COVID-19 epidemic across the Masovian Voivodeship on suspected stroke patients’ baseline characteristics, prehospital vital parameters, clinical and neurological status, emergency procedures performed on the prehospital phase and EMS processing times. Between 1 April 2019 and 30 April 2021, the study population included 18,922 adult suspected stroke patients who were treated by EMS teams, with 18,641 admitted to the emergency departments. The overall number of suspected stroke patients treated by EMS remained unchanged during COVID-19 compared to the pre-COVID-19 period; however, the average time from call to hospital admission increased by 15 min.
Szarpak, Luiza; Filipiak, Krzysztof J.; Gasecka, Aleksandra; Gawel, Wladyslaw; Koziel, Dorota; Jaguszewski, Milosz J.; Chmielewski, Jaroslaw; Gozhenko, Anatolii; Bielski, Karol; Wroblewski, Pawel; Savytskyi, Ivan; Szarpak, Lukasz; Rafique, Zubaid
Vitamin D supplementation to treat SARS-CoV-2 positive patients. Evidence from meta-analysis Journal Article
In: Cardiology Journal, vol. 29, no. 2, pp. 188–196, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{szarpak_vitamin_2022,
title = {Vitamin D supplementation to treat SARS-CoV-2 positive patients. Evidence from meta-analysis},
author = {Luiza Szarpak and Krzysztof J. Filipiak and Aleksandra Gasecka and Wladyslaw Gawel and Dorota Koziel and Milosz J. Jaguszewski and Jaroslaw Chmielewski and Anatolii Gozhenko and Karol Bielski and Pawel Wroblewski and Ivan Savytskyi and Lukasz Szarpak and Zubaid Rafique},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/85559},
doi = {10.5603/cj.a2021.0122},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-04-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {2},
pages = {188–196},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Meyer-Szary, Jarosław; Luis, Marlon Souza; Mikulski, Szymon; Patel, Agastya; Schulz, Finn; Tretiakow, Dmitry; Fercho, Justyna; Jaguszewska, Kinga; Frankiewicz, Mikołaj; Pawłowska, Ewa; Targoński, Radosław; Szarpak, Łukasz; Dądela, Katarzyna; Sabiniewicz, Robert; Kwiatkowska, Joanna
The Role of 3D Printing in Planning Complex Medical Procedures and Training of Medical Professionals—Cross-Sectional Multispecialty Review Journal Article
In: International Journal of Environmental Research and Public Health, vol. 19, no. 6, pp. 3331, 2022, ISSN: 1660-4601, (Publisher: MDPI AG).
@article{meyer-szary_role_2022,
title = {The Role of 3D Printing in Planning Complex Medical Procedures and Training of Medical Professionals—Cross-Sectional Multispecialty Review},
author = {Jarosław Meyer-Szary and Marlon Souza Luis and Szymon Mikulski and Agastya Patel and Finn Schulz and Dmitry Tretiakow and Justyna Fercho and Kinga Jaguszewska and Mikołaj Frankiewicz and Ewa Pawłowska and Radosław Targoński and Łukasz Szarpak and Katarzyna Dądela and Robert Sabiniewicz and Joanna Kwiatkowska},
url = {https://www.mdpi.com/1660-4601/19/6/3331},
doi = {10.3390/ijerph19063331},
issn = {1660-4601},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {International Journal of Environmental Research and Public Health},
volume = {19},
number = {6},
pages = {3331},
abstract = {Medicine is a rapidly-evolving discipline, with progress picking up pace with each passing decade. This constant evolution results in the introduction of new tools and methods, which in turn occasionally leads to paradigm shifts across the affected medical fields. The following review attempts to showcase how 3D printing has begun to reshape and improve processes across various medical specialties and where it has the potential to make a significant impact. The current state-of-the-art, as well as real-life clinical applications of 3D printing, are reflected in the perspectives of specialists practicing in the selected disciplines, with a focus on pre-procedural planning, simulation (rehearsal) of non-routine procedures, and on medical education and training. A review of the latest multidisciplinary literature on the subject offers a general summary of the advances enabled by 3D printing. Numerous advantages and applications were found, such as gaining better insight into patient-specific anatomy, better pre-operative planning, mock simulated surgeries, simulation-based training and education, development of surgical guides and other tools, patient-specific implants, bioprinted organs or structures, and counseling of patients. It was evident that pre-procedural planning and rehearsing of unusual or difficult procedures and training of medical professionals in these procedures are extremely useful and transformative.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Medicine is a rapidly-evolving discipline, with progress picking up pace with each passing decade. This constant evolution results in the introduction of new tools and methods, which in turn occasionally leads to paradigm shifts across the affected medical fields. The following review attempts to showcase how 3D printing has begun to reshape and improve processes across various medical specialties and where it has the potential to make a significant impact. The current state-of-the-art, as well as real-life clinical applications of 3D printing, are reflected in the perspectives of specialists practicing in the selected disciplines, with a focus on pre-procedural planning, simulation (rehearsal) of non-routine procedures, and on medical education and training. A review of the latest multidisciplinary literature on the subject offers a general summary of the advances enabled by 3D printing. Numerous advantages and applications were found, such as gaining better insight into patient-specific anatomy, better pre-operative planning, mock simulated surgeries, simulation-based training and education, development of surgical guides and other tools, patient-specific implants, bioprinted organs or structures, and counseling of patients. It was evident that pre-procedural planning and rehearsing of unusual or difficult procedures and training of medical professionals in these procedures are extremely useful and transformative.
Denegri, Andrea; Sola, Matteo; Morelli, Marianna; Farioli, Francesco; Tosetti, Alberto; D’Arienzo, Matteo; Savorani, Fulvio; Pezzuto, Giuseppe; Boriani, Giuseppe; Szarpak, Lukasz; Magnani, Giulia
Arrhythmias in COVID-19/SARS-CoV-2 Pneumonia Infection: Prevalence and Implication for Outcomes Journal Article
In: Journal of Clinical Medicine, vol. 11, no. 5, pp. 1463, 2022, ISSN: 2077-0383, (Publisher: MDPI AG).
@article{denegri_arrhythmias_2022,
title = {Arrhythmias in COVID-19/SARS-CoV-2 Pneumonia Infection: Prevalence and Implication for Outcomes},
author = {Andrea Denegri and Matteo Sola and Marianna Morelli and Francesco Farioli and Alberto Tosetti and Matteo D’Arienzo and Fulvio Savorani and Giuseppe Pezzuto and Giuseppe Boriani and Lukasz Szarpak and Giulia Magnani},
url = {https://www.mdpi.com/2077-0383/11/5/1463},
doi = {10.3390/jcm11051463},
issn = {2077-0383},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {Journal of Clinical Medicine},
volume = {11},
number = {5},
pages = {1463},
abstract = {Arrhythmias (ARs) are potential cardiovascular complication of COVID-19 but may also have a prognostic role. The aim of this study was to explore the prevalence and impact of cardiac ARs in hospitalized COVID-19 patients. All-comer patients admitted to the emergency department of Modena University Hospital from 16 March to 31 December 2020 and diagnosed with COVID-19 pneumonia infection were included in the study. The primary endpoint was 30-day mortality. Out of 902 patients, 637 (70.6%) presented a baseline 12-lead ECG registration; of these, 122 (19.2%) were diagnosed with ARs. Atrial fibrillation (AF, 40.2%) was the most frequent AR detected. The primary endpoint (30-day mortality) occurred in 33.6% (p < 0.001). AR-patients presented an almost 3-fold risk of mortality compared to non-AR-patients at 30d (Adj. OR = 2.8, 95%CI: 1.8–4.3, p < 0.001). After adjustment for significant baseline characteristics selected by a stepwise backward selection, AR-patients remained at increased risk of mortality (Adj. HR = 2.0, 95%CI: 1.9–2.3, p < 0.001). Sub-group analysis revealed that among ARs patients, those with AF at admission presented the highest risk of 30-day mortality (Adj. HR = 3.1, 95%CI: 2.0–4.9, p < 0.001). In conclusion, ARs are a quite common manifestation in COVID-19 patients, who are burdened by even worse prognosis. AR patients with AF presented the highest risk of mortality; thus, these patients may benefit from a more aggressive secondary preventive therapy and a closer follow up.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Arrhythmias (ARs) are potential cardiovascular complication of COVID-19 but may also have a prognostic role. The aim of this study was to explore the prevalence and impact of cardiac ARs in hospitalized COVID-19 patients. All-comer patients admitted to the emergency department of Modena University Hospital from 16 March to 31 December 2020 and diagnosed with COVID-19 pneumonia infection were included in the study. The primary endpoint was 30-day mortality. Out of 902 patients, 637 (70.6%) presented a baseline 12-lead ECG registration; of these, 122 (19.2%) were diagnosed with ARs. Atrial fibrillation (AF, 40.2%) was the most frequent AR detected. The primary endpoint (30-day mortality) occurred in 33.6% (p < 0.001). AR-patients presented an almost 3-fold risk of mortality compared to non-AR-patients at 30d (Adj. OR = 2.8, 95%CI: 1.8–4.3, p < 0.001). After adjustment for significant baseline characteristics selected by a stepwise backward selection, AR-patients remained at increased risk of mortality (Adj. HR = 2.0, 95%CI: 1.9–2.3, p < 0.001). Sub-group analysis revealed that among ARs patients, those with AF at admission presented the highest risk of 30-day mortality (Adj. HR = 3.1, 95%CI: 2.0–4.9, p < 0.001). In conclusion, ARs are a quite common manifestation in COVID-19 patients, who are burdened by even worse prognosis. AR patients with AF presented the highest risk of mortality; thus, these patients may benefit from a more aggressive secondary preventive therapy and a closer follow up.
Tazerji, Sina Salajegheh; Shahabinejad, Fatemeh; Tokasi, Mahya; Rad, Mohammad Ali; Khan, Muhammad Sajjad; Safdar, Muhammad; Filipiak, Krzysztof J.; Szarpak, Lukasz; Dzieciatkowski, Tomasz; Jurgiel, Jan; Duarte, Phelipe Magalhães; Rahman, Md. Tanvir; Sobur, Md. Abdus; Islam, Md. Saiful; Ahmed, Adnan; Shaheen, Mohamed N. F.; Shehata, Awad A.; Gharieb, Rasha; Fawzy, Mohamed; Malik, Yashpal Singh; Jaganathasamy, Nagaraj; Rajendran, Vinodhkumar Obli; Subbaram, Kannan; Ali, P Shaik Syed; Ali, Sheeza; Rehman, Saif Ur; Ozaslan, Mehmet; Khan, Gulfaraz; Saeed, Muhammad; Younas, Umair; Imran, Safdar; Junejo, Yasmeen; Arabkarami, Parmida; Hogan, Unarose; Rodriguez-Morales, Alfonso J.
Global data analysis and risk factors associated with morbidity and mortality of COVID-19 Journal Article
In: Gene Reports, vol. 26, pp. 101505, 2022, ISSN: 2452-0144, (Publisher: Elsevier BV).
@article{tazerji_global_2022,
title = {Global data analysis and risk factors associated with morbidity and mortality of COVID-19},
author = {Sina Salajegheh Tazerji and Fatemeh Shahabinejad and Mahya Tokasi and Mohammad Ali Rad and Muhammad Sajjad Khan and Muhammad Safdar and Krzysztof J. Filipiak and Lukasz Szarpak and Tomasz Dzieciatkowski and Jan Jurgiel and Phelipe Magalhães Duarte and Md. Tanvir Rahman and Md. Abdus Sobur and Md. Saiful Islam and Adnan Ahmed and Mohamed N. F. Shaheen and Awad A. Shehata and Rasha Gharieb and Mohamed Fawzy and Yashpal Singh Malik and Nagaraj Jaganathasamy and Vinodhkumar Obli Rajendran and Kannan Subbaram and P Shaik Syed Ali and Sheeza Ali and Saif Ur Rehman and Mehmet Ozaslan and Gulfaraz Khan and Muhammad Saeed and Umair Younas and Safdar Imran and Yasmeen Junejo and Parmida Arabkarami and Unarose Hogan and Alfonso J. Rodriguez-Morales},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2452014422000139},
doi = {10.1016/j.genrep.2022.101505},
issn = {2452-0144},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {Gene Reports},
volume = {26},
pages = {101505},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Peacock, Frank W.; Rafique, Zubaid; Ladny, Jerzy R.; Nadolny, Klaudiusz; Malysz, Marek; Dabrowski, Marek; Chirico, Francesco; Smereka, Jacek
Comparison of Vie Scope® and Macintosh laryngoscopes for intubation during resuscitation by paramedics wearing personal protective equipment Journal Article
In: The American Journal of Emergency Medicine, vol. 53, pp. 122–126, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{szarpak_comparison_2022,
title = {Comparison of Vie Scope® and Macintosh laryngoscopes for intubation during resuscitation by paramedics wearing personal protective equipment},
author = {Lukasz Szarpak and Frank W. Peacock and Zubaid Rafique and Jerzy R. Ladny and Klaudiusz Nadolny and Marek Malysz and Marek Dabrowski and Francesco Chirico and Jacek Smereka},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721010482},
doi = {10.1016/j.ajem.2021.12.069},
issn = {0735-6757},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {53},
pages = {122–126},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Pruc, Michal; Jaguszewski, Milosz Jaroslaw
COVID-19 in pediatric patient Journal Article
In: European Journal of Pediatrics, vol. 181, no. 3, pp. 1299–1299, 2022, ISSN: 0340-6199, 1432-1076, (Publisher: Springer Science and Business Media LLC).
@article{szarpak_covid-19_2022,
title = {COVID-19 in pediatric patient},
author = {Lukasz Szarpak and Michal Pruc and Milosz Jaroslaw Jaguszewski},
url = {https://link.springer.com/10.1007/s00431-021-04257-y},
doi = {10.1007/s00431-021-04257-y},
issn = {0340-6199, 1432-1076},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {European Journal of Pediatrics},
volume = {181},
number = {3},
pages = {1299–1299},
note = {Publisher: Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Peacock, Frank W.; Dzieciatkowski, Tomasz; Chirico, Francesco; Szarpak, Lukasz
Self-testing with antigen tests as a method for reduction SARS-CoV-2 Journal Article
In: The American Journal of Emergency Medicine, vol. 53, pp. 274–275, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{peacock_self-testing_2022,
title = {Self-testing with antigen tests as a method for reduction SARS-CoV-2},
author = {Frank W. Peacock and Tomasz Dzieciatkowski and Francesco Chirico and Lukasz Szarpak},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721003855},
doi = {10.1016/j.ajem.2021.05.010},
issn = {0735-6757},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {53},
pages = {274–275},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Ruetzler, Kurt; Figatowski, Tomasz; Pruc, Michal; Gasecka, Aleksandra; Jaguszewski, Milosz J.
Efficacy and safety of prasugrel and clopidogrel in st-segment elevation myocardial infarction in prehospital setting Journal Article
In: The American Journal of Emergency Medicine, vol. 53, pp. 254–255, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{szarpak_efficacy_2022,
title = {Efficacy and safety of prasugrel and clopidogrel in st-segment elevation myocardial infarction in prehospital setting},
author = {Lukasz Szarpak and Kurt Ruetzler and Tomasz Figatowski and Michal Pruc and Aleksandra Gasecka and Milosz J. Jaguszewski},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721003302},
doi = {10.1016/j.ajem.2021.04.044},
issn = {0735-6757},
year = {2022},
date = {2022-03-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {53},
pages = {254–255},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Kleczkowska, Patrycja
Chimeric Structures in Mental Illnesses—“Magic” Molecules Specified for Complex Disorders Journal Article
In: International Journal of Molecular Sciences, vol. 23, no. 7, pp. 3739, 2022, ISSN: 1422-0067.
@article{kleczkowska_chimeric_2022,
title = {Chimeric Structures in Mental Illnesses—“Magic” Molecules Specified for Complex Disorders},
author = {Patrycja Kleczkowska},
url = {https://www.mdpi.com/1422-0067/23/7/3739},
doi = {10.3390/ijms23073739},
issn = {1422-0067},
year = {2022},
date = {2022-03-01},
urldate = {2024-10-28},
journal = {International Journal of Molecular Sciences},
volume = {23},
number = {7},
pages = {3739},
abstract = {Mental health problems cover a wide spectrum of diseases, including mild to moderate anxiety, depression, alcohol/drug use disorders, as well as bipolar disorder and schizophrenia. Pharmacological treatment seems to be one of the most effective opportunities to recover function efficiently and satisfactorily. However, such disorders are complex as several target points are involved. This results in a necessity to combine different types of drugs to obtain the necessary therapeutic goals. There is a need to develop safer and more effective drugs. Considering that mental illnesses share multifactorial processes, the paradigm of one treatment with multiple modes of action rather than single-target strategies would be more effective for successful therapies. Therefore, hybrid molecules that combine two pharmacophores in one entity show promise, as they possess the desired therapeutic index with a small off-target risk. This review aims to provide information on chimeric structures designed for mental disorder therapy (i.e., schizophrenia and depression), and new types of drug candidates currently being tested. In addition, a discussion on some benefits and limitations of multifunctional, bivalent drug candidates is also given.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mental health problems cover a wide spectrum of diseases, including mild to moderate anxiety, depression, alcohol/drug use disorders, as well as bipolar disorder and schizophrenia. Pharmacological treatment seems to be one of the most effective opportunities to recover function efficiently and satisfactorily. However, such disorders are complex as several target points are involved. This results in a necessity to combine different types of drugs to obtain the necessary therapeutic goals. There is a need to develop safer and more effective drugs. Considering that mental illnesses share multifactorial processes, the paradigm of one treatment with multiple modes of action rather than single-target strategies would be more effective for successful therapies. Therefore, hybrid molecules that combine two pharmacophores in one entity show promise, as they possess the desired therapeutic index with a small off-target risk. This review aims to provide information on chimeric structures designed for mental disorder therapy (i.e., schizophrenia and depression), and new types of drug candidates currently being tested. In addition, a discussion on some benefits and limitations of multifunctional, bivalent drug candidates is also given.
Safiejko, Kamil; Tarkowski, Radoslaw; Kozlowski, Tomasz Piotr; Koselak, Maciej; Jachimiuk, Marcin; Tarasik, Aleksander; Pruc, Michal; Smereka, Jacek; Szarpak, Lukasz
Safety and Efficacy of Indocyanine Green in Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis of 11,047 Patients Journal Article
In: Cancers, vol. 14, no. 4, pp. 1036, 2022, ISSN: 2072-6694, (Publisher: MDPI AG).
@article{safiejko_safety_2022,
title = {Safety and Efficacy of Indocyanine Green in Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis of 11,047 Patients},
author = {Kamil Safiejko and Radoslaw Tarkowski and Tomasz Piotr Kozlowski and Maciej Koselak and Marcin Jachimiuk and Aleksander Tarasik and Michal Pruc and Jacek Smereka and Lukasz Szarpak},
url = {https://www.mdpi.com/2072-6694/14/4/1036},
doi = {10.3390/cancers14041036},
issn = {2072-6694},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cancers},
volume = {14},
number = {4},
pages = {1036},
abstract = {Despite the technological advances and improved surgical skills, the incidence of anastomotic leakage following colorectal cancer surgery still ranges from 4% to 19%. Therefore, we performed a systematic review and meta-analysis to evaluate the efficacy and safety of indocyanine green (ICG) use in colorectal cancer surgery. An online search of the Embase, MEDLINE, and Cochrane Central Register of Controlled Trials (CENTRAL) databases (from inception to 10 November 2021) was performed, in addition to manual screening. Thirty-two studies involving 11,047 patients were considered eligible for the meta-analysis. The anastomotic leak rate in the ICG and non-ICG groups varied and amounted to 3.7% vs. 7.6%, respectively (RR = 0.46; 95% CI: 0.39–0.56; p < 0.001). The rate in randomized controlled trials (RCTs) was 8.1% in the ICG group compared with 12.1% in the non-ICG group (RR = 0.67; 95% CI: 0.46–0.98; p = 0.04). In non-RCTs, it equaled 3.1% vs. 7.3%, respectively (RR = 0.43; 95% CI: 0.35–0.52; p < 0.001). Although the publications encompassed in our meta-analysis present different patients, with different factors influencing the results, a pooled analysis revealed a lower incidence of anastomotic leak in cases with ICG use. There are several other convincing advantages: safety, simplicity, and short time of the method adjustment. The presented meta-analysis indicates ICG perfusion assessment as a tool worth considering to decrease the rate of complications following colorectal surgery—valuable in the context of other, well-known risk factors.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Despite the technological advances and improved surgical skills, the incidence of anastomotic leakage following colorectal cancer surgery still ranges from 4% to 19%. Therefore, we performed a systematic review and meta-analysis to evaluate the efficacy and safety of indocyanine green (ICG) use in colorectal cancer surgery. An online search of the Embase, MEDLINE, and Cochrane Central Register of Controlled Trials (CENTRAL) databases (from inception to 10 November 2021) was performed, in addition to manual screening. Thirty-two studies involving 11,047 patients were considered eligible for the meta-analysis. The anastomotic leak rate in the ICG and non-ICG groups varied and amounted to 3.7% vs. 7.6%, respectively (RR = 0.46; 95% CI: 0.39–0.56; p < 0.001). The rate in randomized controlled trials (RCTs) was 8.1% in the ICG group compared with 12.1% in the non-ICG group (RR = 0.67; 95% CI: 0.46–0.98; p = 0.04). In non-RCTs, it equaled 3.1% vs. 7.3%, respectively (RR = 0.43; 95% CI: 0.35–0.52; p < 0.001). Although the publications encompassed in our meta-analysis present different patients, with different factors influencing the results, a pooled analysis revealed a lower incidence of anastomotic leak in cases with ICG use. There are several other convincing advantages: safety, simplicity, and short time of the method adjustment. The presented meta-analysis indicates ICG perfusion assessment as a tool worth considering to decrease the rate of complications following colorectal surgery—valuable in the context of other, well-known risk factors.
Kaminska, Halla; Wieczorek, Pawel; Zalewski, Grzegorz; Malachowska, Beata; Kucharski, Przemyslaw; Fendler, Wojciech; Szarpak, Lukasz; Jarosz-Chobot, Przemyslawa
Reference Ranges of Glycemic Variability in Infants after Surgery—A Prospective Cohort Study Journal Article
In: Nutrients, vol. 14, no. 4, pp. 740, 2022, ISSN: 2072-6643, (Publisher: MDPI AG).
@article{kaminska_reference_2022,
title = {Reference Ranges of Glycemic Variability in Infants after Surgery—A Prospective Cohort Study},
author = {Halla Kaminska and Pawel Wieczorek and Grzegorz Zalewski and Beata Malachowska and Przemyslaw Kucharski and Wojciech Fendler and Lukasz Szarpak and Przemyslawa Jarosz-Chobot},
url = {https://www.mdpi.com/2072-6643/14/4/740},
doi = {10.3390/nu14040740},
issn = {2072-6643},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Nutrients},
volume = {14},
number = {4},
pages = {740},
abstract = {We aimed to define reference ranges of glycemic variability indices derived from continuous glucose monitoring data for non-diabetic infants during post-operative intensive care treatment after cardiac surgery procedures. We performed a prospective cohort intervention study in a pediatric intensive care unit (PICU). Non-diabetic infants aged 0–12 months after corrective cardiovascular surgery procedures were fitted upon arrival to the PICU with a continuous glucose monitoring system (iPro2, Medtronic, Minneapolis, MN, USA). Thirteen glycemic variability indices were calculated for each patient. Complete recordings of 65 patients were collected on the first postoperative day. During the first three postsurgical days 5%, 24% and 43% of patients experienced at least one hypoglycemia episode, and 40%, 10% and 15%—hyperglycemia episode, respectively, in each day. Due to significant differences between the first postoperative day (mean glycemia 130 ± 31 mg/dL) and the second and third day (105 ± 18 mg/dL, 101 ± 22.2 mg/dL; p < 0.0001), we proposed two separate reference ranges—for the acute and steady state patients. Thus, for individual glucose measurements, we proposed a reference range between 85 and 229 mg/dL and 69 and 149 mg/dL. For the mean daily glucose level, ranges between 122 and 137 mg/dL and 95 and 110 mg/dL were proposed. In conclusion, rt-CGM revealed a very high likelihood of hyperglycemia in the first postsurgical day. The widespread use of CGM systems in a pediatric ICU setting should be considered as a safeguard against dysglycemic episodes; however, reference ranges for those patients should be different to those used in diabetes care.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
We aimed to define reference ranges of glycemic variability indices derived from continuous glucose monitoring data for non-diabetic infants during post-operative intensive care treatment after cardiac surgery procedures. We performed a prospective cohort intervention study in a pediatric intensive care unit (PICU). Non-diabetic infants aged 0–12 months after corrective cardiovascular surgery procedures were fitted upon arrival to the PICU with a continuous glucose monitoring system (iPro2, Medtronic, Minneapolis, MN, USA). Thirteen glycemic variability indices were calculated for each patient. Complete recordings of 65 patients were collected on the first postoperative day. During the first three postsurgical days 5%, 24% and 43% of patients experienced at least one hypoglycemia episode, and 40%, 10% and 15%—hyperglycemia episode, respectively, in each day. Due to significant differences between the first postoperative day (mean glycemia 130 ± 31 mg/dL) and the second and third day (105 ± 18 mg/dL, 101 ± 22.2 mg/dL; p < 0.0001), we proposed two separate reference ranges—for the acute and steady state patients. Thus, for individual glucose measurements, we proposed a reference range between 85 and 229 mg/dL and 69 and 149 mg/dL. For the mean daily glucose level, ranges between 122 and 137 mg/dL and 95 and 110 mg/dL were proposed. In conclusion, rt-CGM revealed a very high likelihood of hyperglycemia in the first postsurgical day. The widespread use of CGM systems in a pediatric ICU setting should be considered as a safeguard against dysglycemic episodes; however, reference ranges for those patients should be different to those used in diabetes care.
Szarpak, Lukasz; Michalski, Tomasz A.; Smereka, Jacek; Gasecka, Aleksandra; Pruc, Michal; Jaguszewski, Milosz J.
Efficacy and safety of ticagrelor use in pre-hospital setting Journal Article
In: The American Journal of Emergency Medicine, vol. 52, pp. 265–266, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{szarpak_efficacy_2022-1,
title = {Efficacy and safety of ticagrelor use in pre-hospital setting},
author = {Lukasz Szarpak and Tomasz A. Michalski and Jacek Smereka and Aleksandra Gasecka and Michal Pruc and Milosz J. Jaguszewski},
url = {https://linkinghub.elsevier.com/retrieve/pii/S073567572100317X},
doi = {10.1016/j.ajem.2021.04.031},
issn = {0735-6757},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {52},
pages = {265–266},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Filipiak, Krzysztof J.; Skwarek, Aleksandra; Pruc, Michal; Rahnama, Mansur; Denegri, Andrea; Jachowicz, Marta; Dawidowska, Malgorzata; Gasecka, Aleksandra; Jaguszewski, Milosz J.; Iskrzycki, Lukasz; Rafique, Zubaid
Outcomes and mortality associated with atrial arrhythmias among patients hospitalized with COVID-19: A systematic review and meta-analysis Journal Article
In: Cardiology Journal, vol. 29, no. 1, pp. 33–43, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{szarpak_outcomes_2022,
title = {Outcomes and mortality associated with atrial arrhythmias among patients hospitalized with COVID-19: A systematic review and meta-analysis},
author = {Lukasz Szarpak and Krzysztof J. Filipiak and Aleksandra Skwarek and Michal Pruc and Mansur Rahnama and Andrea Denegri and Marta Jachowicz and Malgorzata Dawidowska and Aleksandra Gasecka and Milosz J. Jaguszewski and Lukasz Iskrzycki and Zubaid Rafique},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/86860},
doi = {10.5603/cj.a2021.0167},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {33–43},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Pruc, Michal; Filipiak, Krzysztof J.; Popieluch, Julia; Bielski, Andrzej; Jaguszewski, Milosz J.; Gilis-Malinowska, Natasza; Chirico, Francesco; Rafique, Zubaid; Peacock, Frank W.
Myocarditis: A complication of COVID-19 and long-COVID-19 syndrome as a serious threat in modern cardiology Journal Article
In: Cardiology Journal, vol. 29, no. 1, pp. 178–179, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{szarpak_myocarditis_2022,
title = {Myocarditis: A complication of COVID-19 and long-COVID-19 syndrome as a serious threat in modern cardiology},
author = {Lukasz Szarpak and Michal Pruc and Krzysztof J. Filipiak and Julia Popieluch and Andrzej Bielski and Milosz J. Jaguszewski and Natasza Gilis-Malinowska and Francesco Chirico and Zubaid Rafique and Frank W. Peacock},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/85786},
doi = {10.5603/cj.a2021.0155},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {178–179},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Nucera, Gabriella; Chirico, Francesco; Rafique, Zubaid; Gilis-Malinowska, Natasza; Gasecka, Aleksandra; Litvinova, Nataliia; Wang, Benjamin; Ilesanmi, Olayinka S.; Pruc, Michal; Jaguszewski, Milosz J.; Szarpak, Lukasz
Need to update cardiological guidelines to prevent COVID-19 related myocardial infarction and ischemic stroke Journal Article
In: Cardiology Journal, vol. 29, no. 1, pp. 174–175, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{nucera_need_2022,
title = {Need to update cardiological guidelines to prevent COVID-19 related myocardial infarction and ischemic stroke},
author = {Gabriella Nucera and Francesco Chirico and Zubaid Rafique and Natasza Gilis-Malinowska and Aleksandra Gasecka and Nataliia Litvinova and Benjamin Wang and Olayinka S. Ilesanmi and Michal Pruc and Milosz J. Jaguszewski and Lukasz Szarpak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/85361},
doi = {10.5603/cj.a2021.0120},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {174–175},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Szarpak, Lukasz; Savytskyi, Ivan; Pruc, Michal; Gozhenko, Anatolyi; Filipiak, Krzysztof J.; Rafique, Zubaid; Peacock, Frank W.; Ilesanmi, Olayinka S.; Chirico, Francesco
Variant lambda of the severe acute respiratory syndrome coronavirus 2: A serious threat or the beginning of further dangerous mutations Journal Article
In: Cardiology Journal, vol. 29, no. 1, pp. 176–177, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{szarpak_variant_2022,
title = {Variant lambda of the severe acute respiratory syndrome coronavirus 2: A serious threat or the beginning of further dangerous mutations},
author = {Lukasz Szarpak and Ivan Savytskyi and Michal Pruc and Anatolyi Gozhenko and Krzysztof J. Filipiak and Zubaid Rafique and Frank W. Peacock and Olayinka S. Ilesanmi and Francesco Chirico},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/85336},
doi = {10.5603/cj.a2021.0121},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {176–177},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Świeczkowski, Damian; Zdanowski, Szymon; Merks, Piotr; Szarpak, Łukasz; Vaillancourt, Régis; Jaguszewski, Milosz J.
In: Cardiology Journal, vol. 29, no. 1, pp. 133–139, 2022, ISSN: 1898-018X, 1897-5593, (Publisher: VM Media SP. zo.o VM Group SK).
@article{swieczkowski_plague_2022,
title = {The plague of unexpected drug recalls and the pandemic of falsified medications in cardiovascular medicine as a threat to patient safety and global public health: A brief review},
author = {Damian Świeczkowski and Szymon Zdanowski and Piotr Merks and Łukasz Szarpak and Régis Vaillancourt and Milosz J. Jaguszewski},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/70713},
doi = {10.5603/cj.a2020.0168},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-09-17},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {133–139},
note = {Publisher: VM Media SP. zo.o VM Group SK},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Surma, Stanislaw; Filipiak, Krzysztof J.
Inflammation and autoimmunity in atherosclerosis Journal Article
In: Rheumatology, vol. 60, no. 1, pp. 1–3, 2022, ISSN: 0034-6233, 2084-9834.
@article{surma_inflammation_2022,
title = {Inflammation and autoimmunity in atherosclerosis},
author = {Stanislaw Surma and Krzysztof J. Filipiak},
url = {https://reu.termedia.pl/Inflammation-and-autoimmunity-in-atherosclerosis,159713,0,2.html},
doi = {10.5114/reum.2022.113364},
issn = {0034-6233, 2084-9834},
year = {2022},
date = {2022-02-01},
urldate = {2024-10-28},
journal = {Rheumatology},
volume = {60},
number = {1},
pages = {1–3},
abstract = {Atherosclerosis is a process whose onset can be observed even in the foetal period. A number of risk factors, such as hyperlipidaemia, hyperhomocysteinaemia, arterial hypertension, hyperuricaemia, smoking, metabolic syndrome, hypertriglyceridaemia, and diabetes, accelerate the progression of atherosclerotic lesions leading to the development of atherosclerotic cardiovascular disease (ASCVD) [1]. <br />
Atherosclerotic cardiovascular disease is defined as coronary artery disease (CAD), cerebrovascular disease, or peripheral arterial disease of atherosclerotic origin. This disease represents the number one cause of morbidity and mortality worldwide. The number of patients with cardiovascular diseases in the world in 2019 was 523 million, while the number of deaths due to them reached 18.6 million [2].},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Atherosclerosis is a process whose onset can be observed even in the foetal period. A number of risk factors, such as hyperlipidaemia, hyperhomocysteinaemia, arterial hypertension, hyperuricaemia, smoking, metabolic syndrome, hypertriglyceridaemia, and diabetes, accelerate the progression of atherosclerotic lesions leading to the development of atherosclerotic cardiovascular disease (ASCVD) [1]. <br />
Atherosclerotic cardiovascular disease is defined as coronary artery disease (CAD), cerebrovascular disease, or peripheral arterial disease of atherosclerotic origin. This disease represents the number one cause of morbidity and mortality worldwide. The number of patients with cardiovascular diseases in the world in 2019 was 523 million, while the number of deaths due to them reached 18.6 million [2].
Atherosclerotic cardiovascular disease is defined as coronary artery disease (CAD), cerebrovascular disease, or peripheral arterial disease of atherosclerotic origin. This disease represents the number one cause of morbidity and mortality worldwide. The number of patients with cardiovascular diseases in the world in 2019 was 523 million, while the number of deaths due to them reached 18.6 million [2].
Czerniuk, Maciej R.; Surma, Stanisław; Romańczyk, Monika; Nowak, Jacek M.; Wojtowicz, Andrzej; Filipiak, Krzysztof J.
Unexpected Relationships: Periodontal Diseases: Atherosclerosis–Plaque Destabilization? From the Teeth to a Coronary Event Journal Article
In: Biology, vol. 11, no. 2, pp. 272, 2022, ISSN: 2079-7737.
@article{czerniuk_unexpected_2022,
title = {Unexpected Relationships: Periodontal Diseases: Atherosclerosis–Plaque Destabilization? From the Teeth to a Coronary Event},
author = {Maciej R. Czerniuk and Stanisław Surma and Monika Romańczyk and Jacek M. Nowak and Andrzej Wojtowicz and Krzysztof J. Filipiak},
url = {https://www.mdpi.com/2079-7737/11/2/272},
doi = {10.3390/biology11020272},
issn = {2079-7737},
year = {2022},
date = {2022-02-01},
urldate = {2024-10-28},
journal = {Biology},
volume = {11},
number = {2},
pages = {272},
abstract = {Atherosclerotic cardiovascular disease (ASCVD) and periodontal disease (PD) are global health problems. High frequency of ASCVD is associated with the spread of many risk factors, including poor diet, sedentary lifestyle, diabetes, hyperlipidemia, obesity, smoking, hypertension, chronic kidney disease, hypertension, hyperhomocysteinemia, hyperuricemia, excessive stress, virus infection, genetic predisposition, etc. The pathogenesis of ASCVD is complex, while inflammation plays an important role. PD is a chronic, multifactorial inflammatory disease caused by dysbiosis of the oral microbiota, causing the progressive destruction of the bone and periodontal tissues surrounding the teeth. The main etiological factor of PD is the bacteria, which are capable of activating the immune response of the host inducing an inflammatory response. PD is associated with a mixed microbiota, with the evident predominance of anaerobic bacteria and microaerophilic. The “red complex” is an aggregate of three oral bacteria: Tannerella forsythia Treponema denticola and Porphyromonas gingivalis responsible for severe clinical manifestation of PD. ASCVD and PD share a number of risk factors, and it is difficult to establish a causal relationship between these diseases. The influence of PD on ASCVD should be treated as a factor increasing the risk of atherosclerotic plaque destabilization and cardiovascular events. The results of observational studies indicate that PD significantly increases the risk of ASCVD. In interventional studies, PD treatment was found to have a beneficial effect in the prevention and control of ASCVD. This comprehensive review summarizes the current knowledge of the relationship between PD and ASCVD.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Atherosclerotic cardiovascular disease (ASCVD) and periodontal disease (PD) are global health problems. High frequency of ASCVD is associated with the spread of many risk factors, including poor diet, sedentary lifestyle, diabetes, hyperlipidemia, obesity, smoking, hypertension, chronic kidney disease, hypertension, hyperhomocysteinemia, hyperuricemia, excessive stress, virus infection, genetic predisposition, etc. The pathogenesis of ASCVD is complex, while inflammation plays an important role. PD is a chronic, multifactorial inflammatory disease caused by dysbiosis of the oral microbiota, causing the progressive destruction of the bone and periodontal tissues surrounding the teeth. The main etiological factor of PD is the bacteria, which are capable of activating the immune response of the host inducing an inflammatory response. PD is associated with a mixed microbiota, with the evident predominance of anaerobic bacteria and microaerophilic. The “red complex” is an aggregate of three oral bacteria: Tannerella forsythia Treponema denticola and Porphyromonas gingivalis responsible for severe clinical manifestation of PD. ASCVD and PD share a number of risk factors, and it is difficult to establish a causal relationship between these diseases. The influence of PD on ASCVD should be treated as a factor increasing the risk of atherosclerotic plaque destabilization and cardiovascular events. The results of observational studies indicate that PD significantly increases the risk of ASCVD. In interventional studies, PD treatment was found to have a beneficial effect in the prevention and control of ASCVD. This comprehensive review summarizes the current knowledge of the relationship between PD and ASCVD.
Szymański, Filip M.; Mickiewicz, Agnieszka; Dzida, Grzegorz; Gorczyca-Głowacka, Iwona; Kozłowski, Dariusz; Widecka, Krystyna; Krasiński, Zbigniew; Kobayashi, Adam; Hering, Dagmara; Mizia-Stec, Katarzyna; Kasprzak, Jarosław D.; Zubilewicz, Tomasz; Narkiewicz, Krzysztof; Koziński, Marek; Płatek, Anna E.; Ryś-Czaporowska, Anna; Chełstowska, Beata; Grajek, Stefan; Wełnicki, Marcin; Mamcarz, Artur; Barylski, Marcin; Wożakowska-Kapłon, Beata; Jaguszewski, Miłosz J.; Gruchała, Marcin; Filipiak, Krzysztof J.
In: Cardiology Journal, vol. 29, no. 1, pp. 1–26, 2022, ISSN: 1898-018X, 1897-5593.
@article{szymanski_management_2022,
title = {Management of dyslipidemia in Poland: Interdisciplinary Expert Position Statement endorsed by the Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy. The Fourth Declaration of Sopot},
author = {Filip M. Szymański and Agnieszka Mickiewicz and Grzegorz Dzida and Iwona Gorczyca-Głowacka and Dariusz Kozłowski and Krystyna Widecka and Zbigniew Krasiński and Adam Kobayashi and Dagmara Hering and Katarzyna Mizia-Stec and Jarosław D. Kasprzak and Tomasz Zubilewicz and Krzysztof Narkiewicz and Marek Koziński and Anna E. Płatek and Anna Ryś-Czaporowska and Beata Chełstowska and Stefan Grajek and Marcin Wełnicki and Artur Mamcarz and Marcin Barylski and Beata Wożakowska-Kapłon and Miłosz J. Jaguszewski and Marcin Gruchała and Krzysztof J. Filipiak},
url = {https://journals.viamedica.pl/cardiology_journal/article/view/86591},
doi = {10.5603/CJ.a2021.0147},
issn = {1898-018X, 1897-5593},
year = {2022},
date = {2022-02-01},
urldate = {2024-10-28},
journal = {Cardiology Journal},
volume = {29},
number = {1},
pages = {1–26},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gąsecka, Aleksandra; Rzepa, Bartholomew; Skwarek, Aleksandra; Ćwiek, Agata; Pluta, Kinga; Szarpak, Łukasz; Jaguszewski, Miłosz J.; Mazurek, Tomasz; Kochman, Janusz; Opolski, Grzegorz; Filipiak, Krzysztof J.; Gąsecki, Krzysztof
Health-related quality of life increases after first-time acute myocardial infarction: A population-based study Journal Article
In: Slovenian Journal of Public Health, vol. 61, no. 1, pp. 24–31, 2022, ISSN: 1854-2476, (Publisher: Walter de Gruyter GmbH).
@article{gasecka_health-related_2022,
title = {Health-related quality of life increases after first-time acute myocardial infarction: A population-based study},
author = {Aleksandra Gąsecka and Bartholomew Rzepa and Aleksandra Skwarek and Agata Ćwiek and Kinga Pluta and Łukasz Szarpak and Miłosz J. Jaguszewski and Tomasz Mazurek and Janusz Kochman and Grzegorz Opolski and Krzysztof J. Filipiak and Krzysztof Gąsecki},
url = {https://www.sciendo.com/article/10.2478/sjph-2022-0005},
doi = {10.2478/sjph-2022-0005},
issn = {1854-2476},
year = {2022},
date = {2022-01-01},
urldate = {2024-09-17},
journal = {Slovenian Journal of Public Health},
volume = {61},
number = {1},
pages = {24–31},
abstract = {Abstract Introduction Acute myocardial infarction (AMI) affects patients’ health-related quality of life (HRQOL). AMI may decrease HRQOL, thus negatively affecting QOL. However, the improvements in interventional treatment and early rehabilitation after AMI may have a positive effect on HRQOL. Aim We evaluated HRQOL in patients after the first AMI treated in a reference cardiology centre in Poland and assessed which clinical variables affect HRQOL after AMI. Material and methods We prospectively evaluated HRQOL in 60 consecutive patients suffering after their first AMI during the index hospitalisation and again after 6 months, using: (i) MacNew, (ii) World Health Organization Quality of Life (WHOQOL) BREF, and (iii) Short Form (SF) 36. Results As measured by the MacNew questionnaire, global, social, and physical functioning did not change (p≥0.063), whereas emotional functioning improved 6 months after AMI, compared to index hospitalisation (p=0.002). As measured by WHOQOL BREF, physical health, psychological health, and environmental functioning did not change (p≥0.321), whereas social relationships improved 6 months after AMI (p=0.042). As assessed by SF-36, the global HRQOL improved after AMI (p=0.044). Patients with improved HRQOL in SF-36 often had a higher baseline body mass index (p=0.046), dyslipidaemia (p=0.046), and lower left ventricle ejection fraction (LVEF; p=0.013). LVEF<50% was the only variable associated with improved HRQOL in multivariate analysis (OR 4.463, 95% CI 1.045 - 19.059},
note = {Publisher: Walter de Gruyter GmbH},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Abstract Introduction Acute myocardial infarction (AMI) affects patients’ health-related quality of life (HRQOL). AMI may decrease HRQOL, thus negatively affecting QOL. However, the improvements in interventional treatment and early rehabilitation after AMI may have a positive effect on HRQOL. Aim We evaluated HRQOL in patients after the first AMI treated in a reference cardiology centre in Poland and assessed which clinical variables affect HRQOL after AMI. Material and methods We prospectively evaluated HRQOL in 60 consecutive patients suffering after their first AMI during the index hospitalisation and again after 6 months, using: (i) MacNew, (ii) World Health Organization Quality of Life (WHOQOL) BREF, and (iii) Short Form (SF) 36. Results As measured by the MacNew questionnaire, global, social, and physical functioning did not change (p≥0.063), whereas emotional functioning improved 6 months after AMI, compared to index hospitalisation (p=0.002). As measured by WHOQOL BREF, physical health, psychological health, and environmental functioning did not change (p≥0.321), whereas social relationships improved 6 months after AMI (p=0.042). As assessed by SF-36, the global HRQOL improved after AMI (p=0.044). Patients with improved HRQOL in SF-36 often had a higher baseline body mass index (p=0.046), dyslipidaemia (p=0.046), and lower left ventricle ejection fraction (LVEF; p=0.013). LVEF<50% was the only variable associated with improved HRQOL in multivariate analysis (OR 4.463, 95% CI 1.045 - 19.059
Szarpak, Lukasz; Mierzejewska, Malgorzata; Jurek, Jonasz; Kochanowska, Anna; Gasecka, Aleksandra; Truszewski, Zenon; Pruc, Michal; Blek, Natasza; Rafique, Zubaid; Filipiak, Krzysztof J.; Denegri, Andrea; Jaguszewski, Milosz J.
Effect of Coronary Artery Disease on COVID-19—Prognosis and Risk Assessment: A Systematic Review and Meta-Analysis Journal Article
In: Biology, vol. 11, no. 2, pp. 221, 2022, ISSN: 2079-7737, (Publisher: MDPI AG).
@article{szarpak_effect_2022,
title = {Effect of Coronary Artery Disease on COVID-19—Prognosis and Risk Assessment: A Systematic Review and Meta-Analysis},
author = {Lukasz Szarpak and Malgorzata Mierzejewska and Jonasz Jurek and Anna Kochanowska and Aleksandra Gasecka and Zenon Truszewski and Michal Pruc and Natasza Blek and Zubaid Rafique and Krzysztof J. Filipiak and Andrea Denegri and Milosz J. Jaguszewski},
url = {https://www.mdpi.com/2079-7737/11/2/221},
doi = {10.3390/biology11020221},
issn = {2079-7737},
year = {2022},
date = {2022-01-01},
urldate = {2024-09-17},
journal = {Biology},
volume = {11},
number = {2},
pages = {221},
abstract = {Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with pre-existing CAD were shown to have a more severe course of COVID-19, but this association has not been clarified. We performed a meta-analysis to determine the association between CAD and COVID-19 outcomes. We searched Scopus, Medline (PubMed), Web of Science, Embase, and Cochrane databases up to 2 November 2021. There were 62 studies with a total population of 49,286 patients included in the meta-analysis. CAD occurrence in survivor vs. non-survivor groups varied and amounted to 9.2% vs. 22.9%, respectively (OR = 0.33; 95%CI: 0.29 to 0.39; I2 = 70%; p < 0.001). CAD was also associated with increased severity of COVID-19 disease and was (10.8% vs. 5.6%, respectively, for severe vs. non-severe groups (OR = 2.28; 95%CI: 1.59 to 3.27; I2 = 72%; p < 0.001). The role of history of CAD in mortality and severe condition in COVID-19 presents itself as prominent—although a risk of bias in retrospective trials needs to be assessed, in case of our meta-analysis the statistically significant results when it comes to higher mortality among patients with CAD compared to non-CAD patients, a more severe condition observed in patients with CAD, and a visibly more frequent admission to intensive care unit in patients with CAD, it seems that an incidence of cardiovascular events plays a role in COVID-19 prognosis.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with pre-existing CAD were shown to have a more severe course of COVID-19, but this association has not been clarified. We performed a meta-analysis to determine the association between CAD and COVID-19 outcomes. We searched Scopus, Medline (PubMed), Web of Science, Embase, and Cochrane databases up to 2 November 2021. There were 62 studies with a total population of 49,286 patients included in the meta-analysis. CAD occurrence in survivor vs. non-survivor groups varied and amounted to 9.2% vs. 22.9%, respectively (OR = 0.33; 95%CI: 0.29 to 0.39; I2 = 70%; p < 0.001). CAD was also associated with increased severity of COVID-19 disease and was (10.8% vs. 5.6%, respectively, for severe vs. non-severe groups (OR = 2.28; 95%CI: 1.59 to 3.27; I2 = 72%; p < 0.001). The role of history of CAD in mortality and severe condition in COVID-19 presents itself as prominent—although a risk of bias in retrospective trials needs to be assessed, in case of our meta-analysis the statistically significant results when it comes to higher mortality among patients with CAD compared to non-CAD patients, a more severe condition observed in patients with CAD, and a visibly more frequent admission to intensive care unit in patients with CAD, it seems that an incidence of cardiovascular events plays a role in COVID-19 prognosis.
Rogula, Sylwester; Gąsecka, Aleksandra; Mazurek, Tomasz; Navarese, Eliano Pio; Szarpak, Łukasz; Filipiak, Krzysztof J.
Safety and Efficacy of DOACs in Patients with Advanced and End-Stage Renal Disease Journal Article
In: International Journal of Environmental Research and Public Health, vol. 19, no. 3, pp. 1436, 2022, ISSN: 1660-4601, (Publisher: MDPI AG).
@article{rogula_safety_2022,
title = {Safety and Efficacy of DOACs in Patients with Advanced and End-Stage Renal Disease},
author = {Sylwester Rogula and Aleksandra Gąsecka and Tomasz Mazurek and Eliano Pio Navarese and Łukasz Szarpak and Krzysztof J. Filipiak},
url = {https://www.mdpi.com/1660-4601/19/3/1436},
doi = {10.3390/ijerph19031436},
issn = {1660-4601},
year = {2022},
date = {2022-01-01},
urldate = {2024-09-17},
journal = {International Journal of Environmental Research and Public Health},
volume = {19},
number = {3},
pages = {1436},
abstract = {The prevalence of chronic kidney disease (CKD) is increasing due to the aging of the population and multiplication of risk factors, such as hypertension, arteriosclerosis and obesity. Impaired renal function increases both the risk of bleeding and thrombosis. There are two groups of orally administered drugs to prevent thromboembolic events in patients with CKD who require anticoagulation: vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs). Although VKAs remain the first-line treatment in patients with advanced CKD, treatment with VKAs is challenging due to difficulties in maintaining the appropriate anticoagulation level, tendency to accelerate vascular calcification and faster progression of CKD in patients treated with VKAs. On the other hand, the pleiotropic effect of DOACs, including vascular protection and anti-inflammatory properties along with comparable efficacy and safety of treatment with DOACs, compared to VKAs observed in preliminary reports encourages the use of DOACs in patients with CKD. This review summarizes the available data on the efficacy and safety of DOACs in patients with CKD and provides recommendations regarding the choice of the optimal drug and dosage depending on the CKD stage.},
note = {Publisher: MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The prevalence of chronic kidney disease (CKD) is increasing due to the aging of the population and multiplication of risk factors, such as hypertension, arteriosclerosis and obesity. Impaired renal function increases both the risk of bleeding and thrombosis. There are two groups of orally administered drugs to prevent thromboembolic events in patients with CKD who require anticoagulation: vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs). Although VKAs remain the first-line treatment in patients with advanced CKD, treatment with VKAs is challenging due to difficulties in maintaining the appropriate anticoagulation level, tendency to accelerate vascular calcification and faster progression of CKD in patients treated with VKAs. On the other hand, the pleiotropic effect of DOACs, including vascular protection and anti-inflammatory properties along with comparable efficacy and safety of treatment with DOACs, compared to VKAs observed in preliminary reports encourages the use of DOACs in patients with CKD. This review summarizes the available data on the efficacy and safety of DOACs in patients with CKD and provides recommendations regarding the choice of the optimal drug and dosage depending on the CKD stage.
Szarpak, Lukasz; Rafique, Zubaid; Gasecka, Aleksandra; Jaguszewski, Milosz J.; Filipiak, Krzysztof J.
Tirofiban in emergency conditions Journal Article
In: The American Journal of Emergency Medicine, vol. 51, pp. 422–423, 2022, ISSN: 0735-6757, (Publisher: Elsevier BV).
@article{szarpak_tirofiban_2022,
title = {Tirofiban in emergency conditions},
author = {Lukasz Szarpak and Zubaid Rafique and Aleksandra Gasecka and Milosz J. Jaguszewski and Krzysztof J. Filipiak},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721002503},
doi = {10.1016/j.ajem.2021.03.063},
issn = {0735-6757},
year = {2022},
date = {2022-01-01},
urldate = {2024-09-17},
journal = {The American Journal of Emergency Medicine},
volume = {51},
pages = {422–423},
note = {Publisher: Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Pluta, Kinga; Porębska, Kinga; Urbanowicz, Tomasz; Gąsecka, Aleksandra; Olasińska-Wiśniewska, Anna; Targoński, Radosław; Krasińska, Aleksandra; Filipiak, Krzysztof; Jemielity, Marek; Krasiński, Zbigniew
Platelet–Leucocyte Aggregates as Novel Biomarkers in Cardiovascular Diseases Journal Article
In: Biology, vol. 11, no. 2, pp. 224, 2022, ISSN: 2079-7737.
@article{pluta_plateletleucocyte_2022,
title = {Platelet–Leucocyte Aggregates as Novel Biomarkers in Cardiovascular Diseases},
author = {Kinga Pluta and Kinga Porębska and Tomasz Urbanowicz and Aleksandra Gąsecka and Anna Olasińska-Wiśniewska and Radosław Targoński and Aleksandra Krasińska and Krzysztof Filipiak and Marek Jemielity and Zbigniew Krasiński},
url = {https://www.mdpi.com/2079-7737/11/2/224},
doi = {10.3390/biology11020224},
issn = {2079-7737},
year = {2022},
date = {2022-01-01},
urldate = {2024-10-28},
journal = {Biology},
volume = {11},
number = {2},
pages = {224},
abstract = {Platelet–leucocyte aggregates (PLA) are a formation of leucocytes and platelets bound by specific receptors. They arise in the condition of sheer stress, thrombosis, immune reaction, vessel injury, and the activation of leukocytes or platelets. PLA participate in cardiovascular diseases (CVD). Increased levels of PLA were revealed in acute and chronic coronary syndromes, carotid stenosis cardiovascular risk factors. Due to accessible, available, replicable, quick, and low-cost quantifying using flow cytometry, PLA constitute an ideal biomarker for clinical practice. PLA are promising in early diagnosing and estimating prognosis in patients with acute or chronic coronary syndromes treated by percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). PLA were also a reliable marker of platelet activity for monitoring antiplatelet therapy. PLA consist also targets potential therapies in CVD. All of the above potential clinical applications require further studies to validate methods of assay and proof clinical benefits.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Platelet–leucocyte aggregates (PLA) are a formation of leucocytes and platelets bound by specific receptors. They arise in the condition of sheer stress, thrombosis, immune reaction, vessel injury, and the activation of leukocytes or platelets. PLA participate in cardiovascular diseases (CVD). Increased levels of PLA were revealed in acute and chronic coronary syndromes, carotid stenosis cardiovascular risk factors. Due to accessible, available, replicable, quick, and low-cost quantifying using flow cytometry, PLA constitute an ideal biomarker for clinical practice. PLA are promising in early diagnosing and estimating prognosis in patients with acute or chronic coronary syndromes treated by percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). PLA were also a reliable marker of platelet activity for monitoring antiplatelet therapy. PLA consist also targets potential therapies in CVD. All of the above potential clinical applications require further studies to validate methods of assay and proof clinical benefits.
Pruc, Michal; Szarpak, Lukasz
Re: Leg-heel chest compression as an alternative for medical professionals in times of COVID-19 Journal Article
In: The American Journal of Emergency Medicine, vol. 51, pp. 412, 2022, ISSN: 07356757.
@article{pruc_re_2022,
title = {Re: Leg-heel chest compression as an alternative for medical professionals in times of COVID-19},
author = {Michal Pruc and Lukasz Szarpak},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0735675721008548},
doi = {10.1016/j.ajem.2021.10.019},
issn = {07356757},
year = {2022},
date = {2022-01-01},
urldate = {2024-10-28},
journal = {The American Journal of Emergency Medicine},
volume = {51},
pages = {412},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Trojnar, Anna; Domagała-Kulawik, Joanna; Sienkiewicz-Ulita, Anna; Zbytniewski, Marcin; Gryszko, Grzegorz M.; Cackowski, Marcin M.; Dziedzic, Michał; Woźnica, Katarzyna; Orłowski, Tadeusz M.; Dziedzic, Dariusz A.
The clinico-pathological characteristics of surgically treated young women with NSCLC Journal Article
In: Translational Lung Cancer Research; Vol 11, No 12 (December 29, 2022): Translational Lung Cancer Research, 2022.
@article{trojnar_clinico-pathological_2022,
title = {The clinico-pathological characteristics of surgically treated young women with NSCLC},
author = {Anna Trojnar and Joanna Domagała-Kulawik and Anna Sienkiewicz-Ulita and Marcin Zbytniewski and Grzegorz M. Gryszko and Marcin M. Cackowski and Michał Dziedzic and Katarzyna Woźnica and Tadeusz M. Orłowski and Dariusz A. Dziedzic},
url = {https://tlcr.amegroups.org/article/view/70679},
year = {2022},
date = {2022-01-01},
urldate = {2022-01-01},
journal = {Translational Lung Cancer Research; Vol 11, No 12 (December 29, 2022): Translational Lung Cancer Research},
keywords = {},
pubstate = {published},
tppubtype = {article}
}